Across TCGA cell cohorts, CXCR3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CXCR3-associated genes across cancer lineages are CSN2, OR5A1, and PRSS58. Each is linked with CXCR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCR3-to-partner and partner-to-CXCR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCR3→partner) and Y-score (partner→CXCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CSN2 →	+0.104	+5.415	<.001	.004	3	1
SKIN	OR5A1 →	+0.020	+6.022	<.001	.001	3	1
SKIN	PRSS58 →	+0.051	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

CXCR3 survival (RNA) · tumor vs normal (RNA) · all CXCR3 data types