CXCL5

Across TCGA cell cohorts, CXCL5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CXCL5-associated genes across cancer lineages are TAAR1, LYZL2, and C14orf177. Each is linked with CXCL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL5-to-partner and partner-to-CXCL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR1 grouped by CXCL5-low versus CXCL5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL5→partner) and Y-score (partner→CXCL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TAAR1 →	+0.021	+4.922	<.001	.009	3	1
BLOOD_Leukemia	LYZL2 →	+0.033	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	C14orf177 →	+0.052	+4.922	.001	.009	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.012	+5.539	.001	.003	3	1
BLOOD_Leukemia	SPATA31A7 →	+0.021	+5.539	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TAAR1 by CXCL5 expression — BLOOD_Leukemia

Explore this box plot interactively →