CXCL10

Across TCGA patient cohorts, CXCL10 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,390 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CXCL10-associated proteins across cancer lineages are SP110_S380, STAT1, and TAP1. Each is linked with CXCL10 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXCL10-to-partner and partner-to-CXCL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL10 versus SP110_S380 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL10→partner) and Y-score (partner→CXCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SP110_S380 →	+0.637	+1.862	<.001	<.001	3	10
BRCA	STAT1 →	+0.806	+2.328	<.001	<.001	3	10
UCEC	TAP1 →	+0.758	+1.708	<.001	<.001	3	10
UCEC	TAP2 →	+0.850	+1.730	<.001	<.001	3	10
UCEC	TAPBP →	+0.794	+1.735	<.001	<.001	3	10
BRCA	GBP1 →	+1.097	+2.359	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,390 associations by consensus.

CXCL10 vs SP110_S380 — GBM

Explore this scatter interactively →