CXCL10

Across TCGA patient cohorts, CXCL10 protein abundance is significantly associated with the RNA expression of many other genes, with 8,283 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CXCL10-associated genes across cancer lineages are CXCL11, GBP1P1, and EPSTI1. Each is linked with CXCL10 in more than 6 cancer types. Because this analysis shows association rather than direction, both CXCL10-to-partner and partner-to-CXCL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL10 versus CXCL11 in HNSC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL10→partner) and Y-score (partner→CXCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CXCL11 →	+2.805	+1.327	<.001	<.001	3	7
UCEC	GBP1P1 →	+1.490	+0.573	<.001	.005	3	7
HNSC	EPSTI1 →	+1.313	+1.178	<.001	<.001	3	6
UCEC	CXCL9 →	+3.339	+0.997	<.001	<.001	3	6
CCRCC	CXCR2P1 →	+3.849	+1.002	<.001	.006	3	6
UCEC	LINC02195 →	+1.196	+0.541	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,283 associations by consensus.

CXCL10 vs CXCL11 — HNSC

Explore this scatter interactively →