CXCL10

Across TCGA patient cohorts, CXCL10 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,537 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CXCL10-associated proteins across cancer lineages are IFIT2, SAMD9L, and STAT1. Each is linked with CXCL10 in more than 6 cancer types. Because this analysis shows association rather than direction, both CXCL10-to-partner and partner-to-CXCL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL10 versus IFIT2 in HNSC, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL10→partner) and Y-score (partner→CXCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IFIT2 →	+0.918	+1.148	<.001	<.001	3	7
OV	SAMD9L →	+0.691	+0.951	.001	.001	3	6
CCRCC	STAT1 →	+1.346	+1.223	.008	.003	2	7
HNSC	DDX60 →	+0.562	+0.942	<.001	<.001	3	6
HNSC	IFIT3 →	+1.082	+1.226	<.001	<.001	3	6
BRCA	OASL →	+0.671	+0.903	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,537 associations by consensus.

CXCL10 vs IFIT2 — HNSC

Explore this scatter interactively →