CXCL10

Across TCGA cell cohorts, CXCL10 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CXCL10-associated genes across cancer lineages are OR2M5 and CT45A6. Each is linked with CXCL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL10-to-partner and partner-to-CXCL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M5 grouped by CXCL10-low versus CXCL10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL10→partner) and Y-score (partner→CXCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2M5 →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CT45A6 →	+0.021	+5.415	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR2M5 by CXCL10 expression — LARGE_INTESTINE

Explore this box plot interactively →