CWF19L1

Across TCGA cell cohorts, CWF19L1 mutation is significantly associated with the mutation status of many other genes, with 1,800 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CWF19L1-associated genes across cancer lineages are KIAA1586, PTPN4, and DAZAP1. Each is linked with CWF19L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CWF19L1-to-partner and partner-to-CWF19L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIAA1586 grouped by CWF19L1-low versus CWF19L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWF19L1→partner) and Y-score (partner→CWF19L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KIAA1586 →	+2.459	+3.321	.005	.005	1	4
LARGE_INTESTINE	PTPN4 →	+2.652	+3.471	.004	.004	1	3
LARGE_INTESTINE	DAZAP1 →	+2.289	+3.182	.008	.008	1	3
BLOOD_Leukemia	PPP2R5D →	+4.000	+5.050	.008	.008	1	3
BLOOD_Leukemia	RTN2 →	+4.000	+5.050	.008	.008	1	3
BLOOD_Leukemia	FBH1 →	+4.000	+5.050	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,800 associations by consensus.

KIAA1586 by CWF19L1 expression — LARGE_INTESTINE

Explore this box plot interactively →