CWC22

Across TCGA patient cohorts, CWC22 protein abundance is significantly associated with the RNA expression of many other genes, with 15,562 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CWC22-associated genes across cancer lineages are OIP5, CNOT9, and TRAIP. Each is linked with CWC22 in more than 6 cancer types. Because this analysis shows association rather than direction, both CWC22-to-partner and partner-to-CWC22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CWC22 versus OIP5 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWC22→partner) and Y-score (partner→CWC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OIP5 →	+0.690	+0.204	<.001	<.001	3	7
UCEC	CNOT9 →	+0.475	+0.176	<.001	.006	3	7
UCEC	TRAIP →	+1.395	+0.187	<.001	.002	3	7
GBM	PRC1 →	+0.402	+0.237	<.001	<.001	3	7
UCEC	BEND3 →	+0.618	+0.185	<.001	<.001	3	7
UCEC	MCM4 →	+1.100	+0.215	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,562 associations by consensus.

CWC22 vs OIP5 — HNSC

Explore this scatter interactively →