CUTA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CUTA protein abundance is significantly associated with the RNA expression of many other genes, with 9,519 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CUTA-associated genes across cancer lineages are ZSCAN16-AS1, F8, and RXRB. Each is linked with CUTA in more than 4 cancer types. Because this analysis shows association rather than direction, both CUTA-to-partner and partner-to-CUTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUTA versus ZSCAN16-AS1 in OV, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUTA→partner) and Y-score (partner→CUTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZSCAN16-AS1 →+0.303+0.237.005.00835
BRCAF8 →+0.611+0.330.002.00235
OVRXRB →+0.653+0.536<.001<.00134
GBMATP6V1G2 →+0.755+0.198.002.00134
HNSCCHRDL1 →+1.398+0.376<.001.00234
LSCCC7 →+1.476+0.208<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,519 associations by consensus.

CUTA vs ZSCAN16-AS1 — OV

Per-sample scatter of CUTA vs ZSCAN16-AS1 in OV (Pearson r = 0.29).

Explore this scatter interactively →

Exploration