CUTA

Across TCGA pan-cancer cohorts, CUTA RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated CUTA data layer compared with 3 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CUTA RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CUTA expression acts as an unfavorable survival marker, although some lineages such as LUAD and UVM show a favorable association.

LUAD, UVM, and KIRC are the cancer types where CUTA RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.536	0.136	<.001	78	view →
UVM	DFS	Tertile	II,III,IV	0.943	0.525	<.001	72	view →
KIRC	DFS	Tertile	All	0.723	0.491	<.001	45	view →
ACC	DFS	Tertile	All	0.233	0.743	<.001	36	view →
LIHC	DFS	Median	All	0.475	0.609	.002	29	view →
THYM	OS	Median	All	1.000	0.920	.011	27	view →
UCS	DFS	Quartile	III,IV	0.199	0.506	.003	24	view →
PAAD	DFS	Tertile	All	0.430	0.173	.010	24	view →
COAD	OS	Median	All	0.808	0.932	.002	21	view →
KICH	DFS	Median	All	0.694	1.000	.008	20	view →
KIRP	OS	Quartile	III,IV	0.418	0.831	.007	19	view →
READ	OS	Median	II,III,IV	0.973	0.857	.007	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

CUTA–LUAD (DFS)

Open the LUAD breakdown →