CUL9

Across TCGA patient cohorts, CUL9 protein abundance is significantly associated with the RNA expression of many other genes, with 15,972 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CUL9-associated genes across cancer lineages are CDC5L, CXCL2, and USB1. Each is linked with CUL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both CUL9-to-partner and partner-to-CUL9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL9 versus CDC5L in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL9→partner) and Y-score (partner→CUL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDC5L →	+0.455	+0.305	.003	<.001	3	3
PDAC	CXCL2 →	+0.905	+0.457	<.001	<.001	3	2
BRCA	USB1 →	-0.589	-0.311	<.001	<.001	3	2
BRCA	OARD1 →	+0.620	+0.420	<.001	<.001	3	2
BRCA	MEA1 →	+0.529	+0.268	<.001	.002	3	2
LSCC	KLC4 →	+0.560	+0.326	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,972 associations by consensus.

CUL9 vs CDC5L — LSCC

Explore this scatter interactively →