CUL4B

Across TCGA patient cohorts, CUL4B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,760 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CUL4B-associated proteins across cancer lineages are HNRNPH2, PHF6, and HTATSF1. Each is linked with CUL4B in more than 6 cancer types. Because this analysis shows association rather than direction, both CUL4B-to-partner and partner-to-CUL4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL4B versus HNRNPH2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL4B→partner) and Y-score (partner→CUL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPH2 →	+0.244	+0.396	<.001	.001	3	7
LSCC	PHF6 →	+0.358	+0.453	<.001	<.001	3	6
LSCC	HTATSF1 →	+0.330	+0.491	<.001	<.001	3	6
BRCA	PSMD10 →	+0.285	+0.536	<.001	<.001	3	5
PDAC	RBM12 →	+0.252	+0.268	<.001	.005	3	5
HNSC	NKRF →	+0.502	+0.441	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,760 associations by consensus.

CUL4B vs HNRNPH2 — HNSC

Explore this scatter interactively →