CUL4B

Across TCGA cell cohorts, CUL4B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,164 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CUL4B-associated GO terms across cancer lineages are Negative regulation of adipose tissue development, Monoubiquitinated protein deubiquitination, and Regulation of post-translational protein modification. Each is linked with CUL4B in more than 15 cancer types. Because this analysis shows association rather than direction, both CUL4B-to-partner and partner-to-CUL4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of adipose tissue development grouped by CUL4B-low versus CUL4B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL4B→partner) and Y-score (partner→CUL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of adipose tissue development →	+0.170	+1.070	<.001	<.001	3	16
BLOOD_Lymphoma	Monoubiquitinated protein deubiquitination →	+0.112	+1.200	<.001	<.001	3	14
KIDNEY	Regulation of post-translational protein modification →	+0.061	+0.983	<.001	.001	3	14
OESOPHAGUS	Transport of virus →	+0.204	+1.187	<.001	<.001	3	13
URINARY_TRACT	Regulation of cytokinesis →	+0.075	+1.200	<.001	<.001	3	13
OESOPHAGUS	Intracellular transport of virus →	+0.204	+1.187	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,164 associations by consensus.

Negative regulation of adipose tissue development by CUL4B expression — PANCREAS

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