CUL4AP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CUL4AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,599 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CUL4AP1-associated GO terms across cancer lineages are Telomerase RNA localization, Endoplasmic reticulum organization, and DNA conformation change. Each is linked with CUL4AP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CUL4AP1-to-partner and partner-to-CUL4AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase RNA localization grouped by CUL4AP1-low versus CUL4AP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL4AP1→partner) and Y-score (partner→CUL4AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADTelomerase RNA localization →+0.113+0.038<.001<.00137
STADEndoplasmic reticulum organization →+0.108+0.037<.001<.00137
STADDNA conformation change →+0.108+0.036<.001<.00137
STADObsolete nuclear-transcribed mRNA catabolic process, exonucleolytic →+0.102+0.035<.001<.00136
STADRegulation of stem cell proliferation →+0.075+0.035<.001<.00136
STADRegulation of endosome size →+0.082+0.075<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,599 associations by consensus.

Telomerase RNA localization by CUL4AP1 expression — STAD

Box plot of Telomerase RNA localization in CUL4AP1-low vs CUL4AP1-high samples in STAD.

Explore this box plot interactively →

Exploration