CUL4AP1

Across TCGA pan-cancer cohorts, CUL4AP1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated CUL4AP1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CUL4AP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CUL4AP1 expression acts as an unfavorable survival marker.

COAD, PAAD, and KIRC are the cancer types where CUL4AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.243	0.796	<.001	90	view →
PAAD	OS	Tertile	All	0.100	0.614	<.001	72	view →
KIRC	DFS	Tertile	II,III,IV	0.196	0.511	.029	48	view →
UCEC	OS	Tertile	All	0.390	0.686	.001	48	view →
LGG	DFS	Tertile	All	0.473	0.837	<.001	30	view →
GBM	OS	Tertile	All	0.074	0.423	<.001	18	view →
LIHC	OS	Tertile	All	0.017	0.784	<.001	18	view →
LUSC	DFS	Tertile	All	0.593	0.796	.031	12	view →
KIRP	OS	Tertile	All	0.262	0.713	.006	12	view →
THYM	DFS	Tertile	All	0.092	0.871	<.001	9	view →
BLCA	DFS	Tertile	III,IV	0.170	0.497	.014	9	view →
BRCA	OS	Tertile	II,III,IV	0.880	0.958	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

CUL4AP1–COAD (OS)

Open the COAD breakdown →