CUL2

Across TCGA patient cohorts, CUL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,031 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CUL2-associated proteins across cancer lineages are RNF40, RNF20, and GMPS. Each is linked with CUL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CUL2-to-partner and partner-to-CUL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL2 versus RNF40 in COAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL2→partner) and Y-score (partner→CUL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNF40 →	+0.219	+0.406	<.001	.001	3	7
BRCA	RNF20 →	+0.243	+0.535	<.001	<.001	3	6
LSCC	GMPS →	+0.697	+0.530	<.001	<.001	3	6
BRCA	HSPA14 →	+0.394	+0.423	<.001	.002	3	6
GBM	WAC →	+0.287	+0.381	<.001	<.001	3	6
LSCC	NCAPG →	+0.604	+0.469	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,031 associations by consensus.

CUL2 vs RNF40 — COAD

Explore this scatter interactively →