CUEDC1

Across TCGA patient cohorts, CUEDC1 mutation is significantly associated with the RNA expression of many other genes, with 2,634 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CUEDC1-associated genes across cancer lineages are NOL12, EGLN1, and NOX3. Each is linked with CUEDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CUEDC1-to-partner and partner-to-CUEDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL12 grouped by CUEDC1-low versus CUEDC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUEDC1→partner) and Y-score (partner→CUEDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOL12 →	+0.313	+3.475	.007	.002	3	2
SKCM	EGLN1 →	+0.798	+3.214	.008	.009	3	2
SKCM	NOX3 →	+0.123	+2.564	.002	.009	3	2
UCEC	OXSM →	+0.437	+2.700	<.001	.005	3	2
UCEC	FAM151B →	+0.300	+2.772	.003	.002	3	2
UCEC	SQSTM1 →	+0.587	+2.425	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,634 associations by consensus.

NOL12 by CUEDC1 expression — UCEC

Explore this box plot interactively →