CUEDC1

Across TCGA pan-cancer cohorts, CUEDC1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated CUEDC1 data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher CUEDC1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CUEDC1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

MESO, LIHC, and KIRC are the cancer types where CUEDC1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.414	0.684	.002	82	view →
LIHC	OS	Median	All	0.417	0.623	<.001	69	view →
KIRC	DFS	Quartile	All	0.797	0.435	<.001	54	view →
BLCA	OS	Tertile	III,IV	0.101	0.501	<.001	51	view →
LAML	DFS	Median	All	0.323	0.601	.003	36	view →
KICH	DFS	Quartile	III,IV	0.282	1.000	.022	35	view →
HNSC	DFS	Tertile	All	0.764	0.652	.015	32	view →
ESCA	OS	Quartile	II,III,IV	0.710	0.371	<.001	32	view →
UCS	DFS	Quartile	II,III,IV	0.777	0.183	.010	22	view →
THCA	DFS	Tertile	III,IV	0.752	0.958	.016	21	view →
UCEC	DFS	Median	IV	0.658	0.282	.017	18	view →
KIRP	DFS	Tertile	IV	0.118	0.664	.021	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

CUEDC1–MESO (OS)

Open the MESO breakdown →