CUEDC1

Across TCGA cell cohorts, CUEDC1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CUEDC1-associated genes across cancer lineages are SRRM4, AGTR2, and OR51T1. Each is linked with CUEDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CUEDC1-to-partner and partner-to-CUEDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRRM4 grouped by CUEDC1-low versus CUEDC1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUEDC1→partner) and Y-score (partner→CUEDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SRRM4 →	+0.066	+3.791	<.001	.007	3	1
OVARY	AGTR2 →	+0.033	+4.339	<.001	.001	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	FABP12 →	+0.085	+5.201	<.001	.006	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	OR2M5 →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SRRM4 by CUEDC1 expression — OVARY

Explore this box plot interactively →