CUBN

Across TCGA patient cohorts, CUBN protein abundance is significantly associated with the RNA expression of many other genes, with 5,404 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CUBN-associated genes across cancer lineages are UPB1, MAPK1, and PRODH. Each is linked with CUBN in more than 1 cancer types. Because this analysis shows association rather than direction, both CUBN-to-partner and partner-to-CUBN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUBN versus UPB1 in CCRCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUBN→partner) and Y-score (partner→CUBN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	UPB1 →	+0.969	+0.454	<.001	<.001	3	1
CCRCC	MAPK1 →	+0.273	+0.453	<.001	<.001	3	1
CCRCC	PRODH →	+1.377	+0.499	<.001	<.001	3	1
CCRCC	SLC35E4 →	-0.221	-0.448	<.001	<.001	3	1
CCRCC	CYTH4 →	-0.454	-0.385	<.001	<.001	3	1
CCRCC	GRK3 →	-0.358	-0.358	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,404 associations by consensus.

CUBN vs UPB1 — CCRCC

Explore this scatter interactively →