CTXN3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CTXN3 mutation is significantly associated with the RNA expression of many other genes, with 768 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTXN3-associated genes across cancer lineages are PPIAP38, TUBBP11, and IGFBP7. Each is linked with CTXN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTXN3-to-partner and partner-to-CTXN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTXN3→partner) and Y-score (partner→CTXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPPIAP38 →+0.190+3.496<.001.00832
COADTUBBP11 →+0.332+5.409<.001.00132
UCECIGFBP7 →-0.660-3.668.003.00132
SKCMEIF3D →+0.549+3.207.003.00932
UCECNDUFA9 →+0.395+3.601.001.00132
UCECFANCA →+0.800+3.721<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Exploration