CTXN1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CTXN1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CTXN1 data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CTXN1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CTXN1 expression acts as an unfavorable survival marker.

UCEC are the cancer types where CTXN1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianAll0.2310.873<.00136view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CTXN1–UCEC (OS)

Kaplan–Meier survival curve for CTXN1 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration