CTXN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CTXN1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTXN1-associated genes across cancer lineages are SLC15A5. Each is linked with CTXN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTXN1-to-partner and partner-to-CTXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by CTXN1-low versus CTXN1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTXN1→partner) and Y-score (partner→CTXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESLC15A5 →+0.023+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SLC15A5 by CTXN1 expression — LARGE_INTESTINE

Box plot of SLC15A5 in CTXN1-low vs CTXN1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration