CTU1

Across TCGA cell cohorts, CTU1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,542 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CTU1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Protein urmylation, and Cytoplasm protein quality control. Each is linked with CTU1 in more than 14 cancer types. Because this analysis shows association rather than direction, both CTU1-to-partner and partner-to-CTU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by CTU1-low versus CTU1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTU1→partner) and Y-score (partner→CTU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.203	+0.788	<.001	<.001	3	15
LIVER	Protein urmylation →	+0.114	+1.061	<.001	<.001	3	14
BONE	Cytoplasm protein quality control →	+0.128	+0.732	<.001	<.001	3	12
BONE	CAMP/PKA signal transduction →	+0.204	+0.906	<.001	<.001	3	12
SKIN	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.084	+0.722	<.001	<.001	3	12
SKIN	Response to dehydroepiandrosterone →	+0.229	+0.694	.003	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,542 associations by consensus.

Pre-mRNA catabolic process by CTU1 expression — BONE

Explore this box plot interactively →