CTTNBP2

Across TCGA patient cohorts, CTTNBP2 mutation is significantly associated with the RNA expression of many other genes, with 5,096 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTTNBP2-associated genes across cancer lineages are PSMD9, EIF2B2, and PIMREG. Each is linked with CTTNBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CTTNBP2-to-partner and partner-to-CTTNBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by CTTNBP2-low versus CTTNBP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2→partner) and Y-score (partner→CTTNBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PSMD9 →	+0.392	+4.045	<.001	<.001	3	4
UCEC	EIF2B2 →	+0.379	+2.705	<.001	<.001	3	4
UCEC	PIMREG →	+0.597	+1.709	.001	<.001	3	4
SKCM	AZGP1 →	-1.297	-2.321	.008	.005	3	4
COAD	IGSF22 →	-0.276	-2.394	.003	.003	3	4
LUAD	SHMT2 →	+0.495	+2.357	.006	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,096 associations by consensus.

PSMD9 by CTTNBP2 expression — SKCM

Explore this box plot interactively →