CTTNBP2

Across TCGA pan-cancer cohorts, CTTNBP2 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CTTNBP2 data layer compared with 11 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CTTNBP2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CTTNBP2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUSC show a favorable association.

KIRC, LUSC, and BLCA are the cancer types where CTTNBP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.752	0.503	<.001	67	view →
LUSC	DFS	Tertile	All	0.820	0.679	.001	59	view →
BLCA	OS	Tertile	IV	0.142	0.415	.006	46	view →
MESO	OS	Quartile	All	0.721	0.397	.001	46	view →
BRCA	DFS	Tertile	III,IV	0.884	0.720	.001	43	view →
LGG	OS	Median	All	0.874	0.741	<.001	36	view →
LUAD	OS	Tertile	II,III,IV	0.867	0.663	.004	31	view →
SCLC	OS	Tertile	II,III,IV	0.417	0.787	.007	21	view →
LIHC	DFS	Tertile	III,IV	0.576	0.270	.004	15	view →
UCEC	OS	Quartile	All	0.574	0.787	.042	12	view →
THYM	DFS	Median	II,III,IV	0.939	0.755	.006	11	view →
STAD	OS	Tertile	All	0.433	0.643	.027	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CTTNBP2–KIRC (DFS)

Open the KIRC breakdown →