CTTNBP2

Across TCGA cell cohorts, CTTNBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,248 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CTTNBP2-associated GO terms across cancer lineages are Regulation of modification of postsynaptic actin cytoskeleton, Presynaptic active zone organization, and Regulation of cardiac muscle tissue development. Each is linked with CTTNBP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CTTNBP2-to-partner and partner-to-CTTNBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of modification of postsynaptic actin cytoskeleton grouped by CTTNBP2-low versus CTTNBP2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2→partner) and Y-score (partner→CTTNBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of modification of postsynaptic actin cytoskeleton →	-0.262	-0.651	<.001	<.001	3	9
OESOPHAGUS	Presynaptic active zone organization →	-0.215	-0.581	<.001	.009	3	7
BREAST	Regulation of cardiac muscle tissue development →	-1.316	-1.166	<.001	.004	3	7
BLOOD_Leukemia	Cytoplasmic translation →	+0.034	+0.828	.001	.001	3	7
OESOPHAGUS	Regulation of postsynaptic membrane potential →	-0.108	-0.434	.004	.006	3	6
SOFT_TISSUE	Regulation of proteasomal protein catabolic process →	+0.047	+0.745	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,248 associations by consensus.

Regulation of modification of postsynaptic actin cytoskeleton by CTTNBP2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →