CTTNBP2

Across TCGA cell cohorts, CTTNBP2 mutation is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTTNBP2-associated genes across cancer lineages are OR13C5, DMRTC1, and OR4D1. Each is linked with CTTNBP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTTNBP2-to-partner and partner-to-CTTNBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C5 grouped by CTTNBP2-low versus CTTNBP2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2→partner) and Y-score (partner→CTTNBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OR13C5 →	+0.351	+3.906	.003	.009	3	3
BLOOD_Leukemia	DMRTC1 →	+0.134	+2.440	.008	.006	3	3
BLOOD_Leukemia	OR4D1 →	+0.117	+2.796	<.001	.003	3	3
BLOOD_Leukemia	OR1L3 →	+0.076	+3.276	<.001	<.001	3	3
BLOOD_Leukemia	KCNG3 →	+0.395	+2.920	<.001	.002	3	2
BLOOD_Leukemia	SNTG2 →	+1.107	+3.977	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

OR13C5 by CTTNBP2 expression — BLOOD_Myeloma

Explore this box plot interactively →