CTSZ

Across TCGA patient cohorts, CTSZ protein abundance is significantly associated with the protein abundance of many other proteins, with 25,469 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTSZ-associated proteins across cancer lineages are AIF1, ARPC5, and CTSA. Each is linked with CTSZ in more than 9 cancer types. Because this analysis shows association rather than direction, both CTSZ-to-partner and partner-to-CTSZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSZ versus AIF1 in GBM, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSZ→partner) and Y-score (partner→CTSZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AIF1 →	+0.785	+0.604	<.001	<.001	3	10
GBM	ARPC5 →	+0.328	+0.510	<.001	<.001	3	9
LSCC	CTSA →	+0.397	+0.429	<.001	<.001	3	9
COAD	CTSB →	+0.858	+0.817	<.001	<.001	3	9
UCEC	CTSH →	+0.791	+0.431	<.001	<.001	3	9
BRCA	SNX3 →	+0.280	+0.309	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,469 associations by consensus.

CTSZ vs AIF1 — GBM

Explore this scatter interactively →