CTSLP8

Across TCGA pan-cancer cohorts, CTSLP8 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CTSLP8 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CTSLP8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CTSLP8 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

COAD, LUSC, and LIHC are the cancer types where CTSLP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	IV	0.159	0.686	<.001	84	view →
LUSC	DFS	Tertile	II,III,IV	0.367	0.725	.002	69	view →
LIHC	OS	Quartile	II,III,IV	0.493	0.758	.002	54	view →
DLBC	OS	Tertile	III,IV	0.154	0.735	.010	40	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	39	view →
CESC	DFS	Tertile	All	0.499	0.761	<.001	36	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
THCA	DFS	Tertile	All	0.722	0.848	.009	36	view →
UVM	OS	Tertile	All	0.899	0.483	.015	32	view →
LUAD	DFS	Tertile	IV	0.484	0.936	.001	30	view →
UCS	DFS	Tertile	All	0.730	0.398	.009	24	view →
READ	OS	Tertile	II,III,IV	0.499	0.867	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CTSLP8–COAD (OS)

Open the COAD breakdown →