CTSLP2

Across TCGA patient cohorts, CTSLP2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTSLP2-associated genes across cancer lineages are RNU6-1082P, RNU6-213P, and RNU6-1026P. Each is linked with CTSLP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTSLP2-to-partner and partner-to-CTSLP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1082P grouped by CTSLP2-low versus CTSLP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSLP2→partner) and Y-score (partner→CTSLP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1082P →	+0.416	+4.551	<.001	.009	3	1
UCEC	RNU6-213P →	+0.548	+4.423	.008	.006	3	1
UCEC	RNU6-1026P →	+0.544	+4.937	<.001	.005	3	1
UCEC	MIR1266 →	+0.469	+4.771	<.001	.006	3	1
UCEC	RPS3AP30 →	+0.127	+4.188	.003	.009	3	1
UCEC	BMS1P13 →	+0.168	+5.184	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

RNU6-1082P by CTSLP2 expression — UCEC

Explore this box plot interactively →