CTSD

Across TCGA patient cohorts, CTSD RNA expression is significantly associated with the protein abundance of many other proteins, with 17,590 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTSD-associated proteins across cancer lineages are CTSL, FKBP15, and IFI30. Each is linked with CTSD in more than 6 cancer types. Because this analysis shows association rather than direction, both CTSD-to-partner and partner-to-CTSD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSD versus CTSL in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSD→partner) and Y-score (partner→CTSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSL →	+0.428	+0.921	<.001	<.001	3	7
GBM	FKBP15 →	+0.239	+0.756	<.001	<.001	3	7
GBM	IFI30 →	+1.025	+0.874	<.001	<.001	3	7
GBM	ITGAX →	+0.544	+0.776	<.001	<.001	3	7
GBM	APOBR →	+0.653	+0.875	<.001	<.001	3	7
GBM	PSAP →	+0.400	+0.544	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,590 associations by consensus.

CTSD vs CTSL — GBM

Explore this scatter interactively →