CTSC

Across TCGA pan-cancer cohorts, CTSC mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CTSC data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CTSC mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CTSC expression acts as an unfavorable survival marker.

COAD, GBM, and LUAD are the cancer types where CTSC mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	III,IV	0.667	1.000	.011	96	view →
GBM	OS	Quartile	All	0.339	0.605	.004	12	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CTSC–COAD (DFS)

Open the COAD breakdown →