CTSC

Across TCGA patient cohorts, CTSC RNA expression is significantly associated with the protein abundance of many other proteins, with 18,357 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTSC-associated proteins across cancer lineages are LCP2, PARP14, and GBP5. Each is linked with CTSC in more than 8 cancer types. Because this analysis shows association rather than direction, both CTSC-to-partner and partner-to-CTSC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSC versus LCP2 in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSC→partner) and Y-score (partner→CTSC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCP2 →	+0.675	+1.293	<.001	<.001	3	9
BRCA	PARP14 →	+0.474	+0.910	<.001	<.001	3	9
BRCA	GBP5 →	+1.135	+0.797	<.001	<.001	3	9
BRCA	SAMHD1 →	+0.465	+0.739	<.001	<.001	3	8
PDAC	ITGB2 →	+0.846	+0.666	<.001	<.001	3	8
BRCA	LYN →	+0.577	+0.848	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,357 associations by consensus.

CTSC vs LCP2 — GBM

Explore this scatter interactively →