CTSB

Across TCGA patient cohorts, CTSB RNA expression is significantly associated with the RNA expression of many other genes, with 17,371 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CTSB-associated genes across cancer lineages are FPR3, PSAP, and CTSD. Each is linked with CTSB in more than 32 cancer types. Because this analysis shows association rather than direction, both CTSB-to-partner and partner-to-CTSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSB versus FPR3 in BLCA, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSB→partner) and Y-score (partner→CTSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FPR3 →	+2.179	+1.472	<.001	<.001	3	33
LAML	PSAP →	+1.688	+1.471	<.001	<.001	3	33
ACC	CTSD →	+1.436	+1.615	<.001	<.001	3	33
ACC	FTH1 →	+1.424	+1.223	<.001	<.001	3	32
LAML	ITGAM →	+2.367	+1.389	<.001	<.001	3	32
DLBC	OSCAR →	+1.691	+1.453	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,371 associations by consensus.

CTSB vs FPR3 — BLCA

Explore this scatter interactively →