CTSB

Across TCGA patient cohorts, CTSB RNA expression is significantly associated with the protein abundance of many other proteins, with 21,351 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTSB-associated proteins across cancer lineages are C1QA, FCER1G, and FNDC3B. Each is linked with CTSB in more than 7 cancer types. Because this analysis shows association rather than direction, both CTSB-to-partner and partner-to-CTSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSB versus C1QA in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSB→partner) and Y-score (partner→CTSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	C1QA →	+0.633	+0.931	<.001	<.001	3	8
GBM	FCER1G →	+0.932	+1.147	<.001	<.001	3	8
BRCA	FNDC3B →	+0.518	+0.671	<.001	<.001	3	8
CCRCC	PLAU →	+0.774	+0.668	<.001	.001	3	8
GBM	NCF2 →	+0.992	+1.182	<.001	<.001	3	8
GBM	NCF4 →	+0.937	+1.253	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,351 associations by consensus.

CTSB vs C1QA — GBM

Explore this scatter interactively →