CTRC

Across TCGA patient cohorts, CTRC protein abundance is significantly associated with the RNA expression of many other genes, with 1,181 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CTRC-associated genes across cancer lineages are REG1A, WASH3P, and RNVU1-3. Each is linked with CTRC in more than 1 cancer types. Because this analysis shows association rather than direction, both CTRC-to-partner and partner-to-CTRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTRC versus REG1A in PDAC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTRC→partner) and Y-score (partner→CTRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	REG1A →	+3.166	+0.925	<.001	<.001	3	2
COAD	WASH3P →	-0.396	-0.798	.001	.004	3	2
COAD	RNVU1-3 →	-0.718	-0.961	.002	.002	3	2
COAD	GSTZ1 →	+0.451	+0.711	.006	.006	3	1
COAD	PSME2 →	+0.617	+0.851	.002	.001	3	1
COAD	EPPIN →	-0.053	-0.952	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,181 associations by consensus.

CTRC vs REG1A — PDAC

Explore this scatter interactively →