CTRC

Across TCGA cell cohorts, CTRC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,024 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CTRC-associated GO terms across cancer lineages are Positive regulation of intracellular protein transport, Regulation of nucleocytoplasmic transport, and Regulation of RNA splicing. Each is linked with CTRC in more than 6 cancer types. Because this analysis shows association rather than direction, both CTRC-to-partner and partner-to-CTRC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular protein transport grouped by CTRC-low versus CTRC-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTRC→partner) and Y-score (partner→CTRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of intracellular protein transport →	+0.059	+0.278	.002	.005	3	7
PANCREAS	Regulation of nucleocytoplasmic transport →	+0.076	+0.336	.001	.005	3	7
BREAST	Regulation of RNA splicing →	+0.066	+0.226	.003	.005	3	7
BONE	Regulation of alternative mRNA splicing, via spliceosome →	+0.106	+0.355	<.001	<.001	3	7
BREAST	Hair follicle placode formation →	+0.061	+0.245	<.001	.002	3	6
PANCREAS	Positive regulation of type 2 mitophagy →	+0.101	+0.298	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

Positive regulation of intracellular protein transport by CTRC expression — PANCREAS

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