CTNNBL1

Across TCGA cell cohorts, CTNNBL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,670 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTNNBL1-associated GO terms across cancer lineages are Regulation of centriole-centriole cohesion, Positive regulation of cell cycle checkpoint, and Spliceosomal tri-snRNP complex assembly. Each is linked with CTNNBL1 in more than 14 cancer types. Because this analysis shows association rather than direction, both CTNNBL1-to-partner and partner-to-CTNNBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole-centriole cohesion grouped by CTNNBL1-low versus CTNNBL1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNBL1→partner) and Y-score (partner→CTNNBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of centriole-centriole cohesion →	+0.202	+0.745	<.001	<.001	3	15
URINARY_TRACT	Positive regulation of cell cycle checkpoint →	+0.166	+1.035	<.001	<.001	3	14
BREAST	Spliceosomal tri-snRNP complex assembly →	+0.106	+0.881	<.001	<.001	3	13
SOFT_TISSUE	Telomere maintenance in response to DNA damage →	+0.087	+0.725	.001	<.001	3	12
SOFT_TISSUE	DNA-templated transcription initiation →	+0.070	+0.904	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Mitotic centrosome separation →	+0.135	+1.041	.004	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

Regulation of centriole-centriole cohesion by CTNNBL1 expression — SOFT_TISSUE

Explore this box plot interactively →