CTNNAL1

Across TCGA pan-cancer cohorts, CTNNAL1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CTNNAL1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CTNNAL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CTNNAL1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where CTNNAL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	1.000	0.549	.003	11	view →
LUAD	DFS	Tertile	All	0.718	1.000	.048	1	view →
LSCC	DFS	Tertile	III,IV	1.000	0.509	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CTNNAL1–CCRCC (DFS)

Open the CCRCC breakdown →