Across TCGA cell cohorts, CTNNA3 mutation is significantly associated with the RNA expression of many other genes, with 1,065 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTNNA3-associated genes across cancer lineages are WFDC12, FADS6, and GSR. Each is linked with CTNNA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTNNA3-to-partner and partner-to-CTNNA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNA3→partner) and Y-score (partner→CTNNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	WFDC12 →	+0.036	+5.169	<.001	.004	3	2
BLOOD_Lymphoma	FADS6 →	+0.029	+3.843	<.001	.007	3	2
LARGE_INTESTINE	GSR →	+0.924	+3.409	<.001	<.001	3	2
OESOPHAGUS	SOX3 →	+0.040	+3.432	.001	.001	3	1
OESOPHAGUS	VWC2 →	+0.053	+3.273	.001	.004	3	1
BLOOD_Lymphoma	CRCT1 →	+0.015	+4.058	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,065 associations by consensus.

Exploration

CTNNA3 survival (RNA) · tumor vs normal (RNA) · all CTNNA3 data types