CTNNA2

Across TCGA patient cohorts, CTNNA2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,480 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTNNA2-associated genes across cancer lineages are PFN1, TSGA10, and APCDD1. Each is linked with CTNNA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTNNA2-to-partner and partner-to-CTNNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTNNA2 versus PFN1 in HNSC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTNNA2→partner) and Y-score (partner→CTNNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PFN1 →	-0.855	-1.036	.006	<.001	3	3
UCEC	TSGA10 →	+0.592	+0.882	.003	.001	3	3
COAD	APCDD1 →	+2.895	+1.655	.002	.004	3	3
UCEC	ENTPD3 →	+1.421	+1.167	<.001	<.001	3	3
UCEC	PELATON →	-0.697	-1.226	<.001	<.001	3	3
UCEC	MPPED2 →	+0.900	+0.729	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,480 associations by consensus.

CTNNA2 vs PFN1 — HNSC

Explore this scatter interactively →