CTHRC1

Across TCGA patient cohorts, CTHRC1 mutation is significantly associated with the RNA expression of many other genes, with 318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTHRC1-associated genes across cancer lineages are OR7E149P, MIR6796, and RNU7-11P. Each is linked with CTHRC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTHRC1-to-partner and partner-to-CTHRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E149P grouped by CTHRC1-low versus CTHRC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTHRC1→partner) and Y-score (partner→CTHRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR7E149P →	+0.060	+3.081	<.001	.001	3	2
LIHC	MIR6796 →	+0.624	+5.268	<.001	.006	3	1
LIHC	RNU7-11P →	+0.625	+5.355	<.001	.005	3	1
LIHC	IGLV3-15 →	+0.202	+5.544	<.001	.004	3	1
LIHC	SLC25A51P3 →	+0.062	+5.355	<.001	.005	3	1
LIHC	CCNG2P1 →	+0.052	+5.108	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

OR7E149P by CTHRC1 expression — UCEC

Explore this box plot interactively →