CTDP1

Across TCGA cell cohorts, CTDP1 mutation is significantly associated with the RNA expression of many other genes, with 443 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTDP1-associated genes across cancer lineages are DEFB134, FAM47B, and GAGE12F. Each is linked with CTDP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CTDP1-to-partner and partner-to-CTDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB134 grouped by CTDP1-low versus CTDP1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTDP1→partner) and Y-score (partner→CTDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DEFB134 →	+0.136	+3.321	<.001	.001	3	3
LUNG_NSCLC_LUSC	FAM47B →	+0.036	+4.643	<.001	.008	3	2
LUNG_NSCLC_LUSC	GAGE12F →	+1.263	+4.643	.002	.008	3	2
LUNG_NSCLC_LUAD	KCNK18 →	+0.014	+4.662	<.001	.005	3	2
BLOOD_Lymphoma	LCN9 →	+0.015	+4.247	<.001	.004	3	2
CNS	DCD →	+0.013	+3.772	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 443 associations by consensus.

DEFB134 by CTDP1 expression — CNS

Explore this box plot interactively →