CTCFL

Across TCGA patient cohorts, CTCFL mutation is significantly associated with the RNA expression of many other genes, with 4,858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTCFL-associated genes across cancer lineages are BCS1L, DUSP12, and SENP3-EIF4A1. Each is linked with CTCFL in more than 3 cancer types. Because this analysis shows association rather than direction, both CTCFL-to-partner and partner-to-CTCFL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCS1L grouped by CTCFL-low versus CTCFL-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTCFL→partner) and Y-score (partner→CTCFL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BCS1L →	+0.317	+1.932	.002	.003	3	4
SKCM	DUSP12 →	+0.585	+2.984	<.001	<.001	3	4
UCEC	SENP3-EIF4A1 →	+0.109	+2.854	<.001	<.001	3	3
COAD	CAB39P1 →	+0.358	+3.317	<.001	.009	3	3
SKCM	RNASEH1-AS1 →	+0.514	+2.341	.001	.003	3	3
UCEC	NCAPG →	+0.578	+1.593	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,858 associations by consensus.

BCS1L by CTCFL expression — SKCM

Explore this box plot interactively →