CTBP1-AS

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CTBP1-AS RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CTBP1-AS data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CTBP1-AS RNA is associated with better overall survival. In most high-consensus cancer types, elevated CTBP1-AS expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and UVM are the cancer types where CTBP1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileAll0.5280.318<.001123view →
SKCMOSTertileIII,IV0.5290.259.00259view →
UVMDFSQuartileIII,IV0.1710.893<.00156view →
UCSDFSMedianIV0.9520.367.00152view →
PAADOSMedianAll0.5130.280<.00148view →
CESCDFSMedianAll0.6690.810.00436view →
OVOSMedianIV0.6020.883.00332view →
LGGDFSMedianAll0.7800.883<.00130view →
KIRPDFSTertileIV0.0430.811.01029view →
BRCAOSQuartileIII,IV0.9500.788.00326view →
KIRCDFSMedianAll0.5670.675.00925view →
BLCAOSQuartileII,III,IV0.7830.654.02211view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CTBP1-AS–HNSC (OS)

Kaplan–Meier survival curve for CTBP1-AS RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration