CTBP1-AS

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CTBP1-AS RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CTBP1-AS’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CTBP1-AS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CTBP1-AS is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

KIRC, LIHC, and BRCA are the cancer types where CTBP1-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CTBP1-AS RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCAllAll+0.206<.0018view →
LIHCFemaleAll+0.288<.0017view →
BRCAFemaleAll−0.245<.0016view →
STADAllAll+0.435.0045view →
COADFemaleAll+0.362.0045view →
KICHAllII,III,IV+0.354.0015view →
THCAAllAll−0.199.0104view →
CHOLAllAll+1.142<.0013view →
PRADAllAll+1.297<.0012view →
KIRPAllIV+0.602.0282view →
LUSCAllAll−0.258.0072view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CTBP1-AS–KIRC

Tumor-vs-normal expression box plot for CTBP1-AS RNA in KIRC.

Open the KIRC breakdown →

Exploration