CT47B1

Across TCGA patient cohorts, CT47B1 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CT47B1-associated genes across cancer lineages are JNK_pT183_Y185, A-Raf_pS299, and ERK2. Each is linked with CT47B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT47B1-to-partner and partner-to-CT47B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CT47B1-low versus CT47B1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT47B1→partner) and Y-score (partner→CT47B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	JNK_pT183_Y185 →	-0.140	-2.978	.018	.036	3	2
UCEC	A-Raf_pS299 →	-0.119	-3.169	.005	.018	3	2
UCEC	ERK2 →	+0.166	+1.874	.016	.049	3	2
UCEC	S6_pS240_S244 →	+0.404	+2.000	.005	.030	3	2
UCEC	Caspase-8 →	-0.252	-3.673	.005	.001	3	2
UCEC	4E-BP1 →	+0.214	+1.904	.028	.029	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

JNK_pT183_Y185 by CT47B1 expression — STAD

Explore this box plot interactively →