CT47B1

Across TCGA cell cohorts, CT47B1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CT47B1-associated genes across cancer lineages are SSMEM1, LCE1C, and MYOD1. Each is linked with CT47B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT47B1-to-partner and partner-to-CT47B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSMEM1 grouped by CT47B1-low versus CT47B1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT47B1→partner) and Y-score (partner→CT47B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.707	.008	.009	3	1
LARGE_INTESTINE	LCE1C →	+0.062	+3.684	.004	.006	3	1
BLOOD_Leukemia	MYOD1 →	+0.022	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KCNA4 →	+0.028	+4.922	<.001	.009	3	1
LUNG_SCLC	PRAMEF11 →	+0.026	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SSMEM1 by CT47B1 expression — LARGE_INTESTINE

Explore this box plot interactively →