CSTF3

Across TCGA patient cohorts, CSTF3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,623 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CSTF3-associated genes across cancer lineages are KIF11, ASPM, and GINS1. Each is linked with CSTF3 in more than 8 cancer types. Because this analysis shows association rather than direction, both CSTF3-to-partner and partner-to-CSTF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTF3 versus KIF11 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF3→partner) and Y-score (partner→CSTF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF11 →	+0.878	+0.185	<.001	<.001	3	9
HNSC	ASPM →	+1.005	+0.231	<.001	<.001	3	9
LUAD	GINS1 →	+0.950	+0.230	<.001	<.001	3	8
COAD	NELFCD →	+0.803	+0.164	<.001	<.001	3	8
UCEC	MRGBP →	+0.836	+0.235	.001	<.001	3	8
GBM	LMNB1 →	+0.878	+0.252	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,623 associations by consensus.

CSTF3 vs KIF11 — UCEC

Explore this scatter interactively →